Completely agree on pickup simulation.
There have been so many comments from people saying "..profiles don't sound like demo's". And this is probably why in most cases.
We have any number of amps, cabinets and effects to use. But the pickups in your guitar will have more influence on what you hear than just about all of these. I've been using a Keyztone Exchange for quite a while and being able to select a different pickup can make a very noticeable difference. They may not be 100% accurate, but still more than worthwhile.
Imagine being able to save a pickup as part of the Kemper rig. For example a Fender rig with a Tele pickup no matter what's in your guitar.
Hmmm, happy to be proved wrong but I'm not sure pickups make that much difference, I think its more subtle. Yes a 60's single coil will sound nothing like an EMG 81 but the difference between a Seymour Blackout's...I change my pickups more for those subtle changes ( bit more drive usually) but driving a cranked amp as volume?