With Helix, Amplifire and Axe FX I used almost always EQ Blocks to tame some frequencies and also did hi/low cuts...
Now with Kemper I actually feel, that there isn't as much nasty frequencies present, that I'd need to cut. Also hi/low cuts doesn't seem to be necessary. I'm speaking about profiles in general. Of course there are profiles, that are very boomy for example, but for the most part I feel that Kemper profiles are much pleasing sounding, than other units Amp sims I have had.
How about you? Do you usually use EQ with Profiles?