Theoretically it should be no different from using the equivalent FX in stomp from.
The only difference might be that you're (usually) limited to the output-level range of your audio interface. If you need more juice than you have feeding the usual reamp input on the rear of the unit, I'm guessing here, but sending the signal to the front input, where guitar-level signals are the expected "norm", might enable you to extract a little more oomph than what may otherwise be the case from a given rig.
Other than for that possible shortcoming, which I'd expect wouldn't manual-titty-fest as being relevant in most situations, you should be good to go... for it!
EDIT: These "</p>" additions incessant-titty-tasting my having to edit every post are becoming just a little anal-knawing... I mean, annoying. Geez, I've really gotta get a handle on my linguistic edumacation. 
The main problem I would expect is latency. It could be a significant problem depending on the DAW, computer, audio interface, etc.
If I'm understanding what you would be trying to do (which I assume is to use the DAW in real time as you're playing the guitar), I think it would still depend upon the speed with which a signal can get into the DAW, processed, and back out. Certainly worth a try.
Agreed. The difference between using the analogue and digital connections on the Kemper, latency-wise, would be in the order of 1ms or thereabouts - hardly significant.
The trick will be for dbidder to do whatever he needs to do to minimise throughput latency, such as pre-mix rendering and bypassing plug-ins.
Keep us posted...
Our pleasure, mate.
