Beside the (useful) suggestions mentioned above:
I think it has a lot to do with the settings of the profiled amp during the profiling process...
My personal taste is not very "mainstream friendly" because I tend to turn the Bass knobs
on my amps way (!) down. (not above 9 or 10 o'clock...)
But a lot of the people out there seem to follow the (unwritten) "all knobs at 12 o'clock" rule...
maybe they think this way: If all knobs are in the middle, I have a "balanced sound" with no frequency too low and no frequency too much...
But in my humble opinion (almost) no amp sounds good this way.
When it comes to commercial profiles, the providers try to fit the taste of the mainstream community because they want
to make money.... nothing wrong with that, as far as your taste is not extraordinary !
Especially high gain sounds tend to overemphasize the low frequency if the bass knob is not turned down...
Sometimes I think that most guitar players try to undercut the frequency of the bass player because they are dreaming of being so "mighty"...
(but maybe that's just layman psychology...)