I've had this same issue with Rig Manager a few months back.
RM is still having the problem where it won't save edited parameters I make to a given rig within RM. Like I'll turn amplifier volume from 0 to 4, then save it. But I'll check that rig a few minutes later and the changes are gone and it's back to 0. Doesn't do this 100% of the time, maybe 1/3 of the time. AND it does the same thing when I manually edit on the Kemper itself - it's like RM sees the changed parameter for a while and then erases the change with the USB connection between hardware and software.
It had this problem a few months ago, and I left the kemper/RM alone for a few months thinking a software update would fix this but it hasn't. Is there a previous RM software that's more reliable? I wanna say about 6 months ago the software worked fine, i can't remember which one that is.
Another thought - i'm editing rigs in 'Local Library', they aren't saved on 'myProfiler' yet. Would RM work better with rigs that are on 'myProfiler'? Super frustrating..please help