Pedal Compressor - where in chain?

I've always run my compressor in front of the Kemper and it sounds really good, but should I be putting it in a loop and assigning it to Effect 1 instead? Wondering if the Kemper sounds better if the Input section is fed the pure guitar signal.

Same question for dirt pedals.

Sorry if this has been discussed already.

Yeah, I'm just wondering if the Kemper input vs the loop will affect the sound, like is there an A/D stage between the input and the first leg of the loop.

In addition to the Lyndhurst compressor, I also run an OCD clone and an Uberschall pedal in front and I'm used to turning them on/off individually.

I think sticking them all in a loop in Effect 1 makes the most sense, so I can turn them all on at once. It consumes a slot, but I usually use that slot for the Kemper compressor if I'm not using the pedalboard, so nothing lost.