Unlike others in the thread, I haven't ever gotten along with a PRS, after 4 tries. I do have 5 LPs. 2 are top end Epiphones, because you can get them Light, 2 are Gibsons, but chambered models, and one is a Gibson LP Special (also light but thinner and with a belly cut).
Tuning can be a problem because of Gibson's headstock angle and string break angle. SO easily fixed with just a little work on the nut. widen the peg side of the string groove, so the string doesn't bind, et voila.
Ca't help with the neck profile. Either you like it or you don't. Though Epiphones have more thinner neck profiles than Gibson LPs. Same thing for upper fret access. You just have to learn to work with what it provides.