I've not found any benefits.. but used mostly in studio environment here for re-amping or additional guitar overdubs.
(No pedals or remote used)
What I would benefit from the most (and I imagine anyone who has one of these racked in the studio) would be a software editor to save bending over to reach to the racks to adjust on a tiny little screen, I would get so much more use out if it... I rarely now and it doesn't get the amount of use it should!